KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HLTF
All Species:
22.42
Human Site:
Y121
Identified Species:
37.95
UniProt:
Q14527
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14527
NP_003062.2
1009
113929
Y121
E
L
A
G
A
L
A
Y
I
M
D
N
K
L
A
Chimpanzee
Pan troglodytes
XP_001138277
1009
113822
Y121
E
L
A
G
A
L
A
Y
I
M
D
N
K
L
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534300
1106
124184
Y220
D
L
A
A
A
L
A
Y
I
M
D
N
K
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q6PCN7
1003
113298
Y121
E
I
A
A
A
V
A
Y
I
M
D
N
K
L
A
Rat
Rattus norvegicus
NP_001099948
974
110023
V108
N
N
V
N
G
N
Q
V
G
H
L
K
R
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508504
884
99044
L98
F
D
K
L
F
E
D
L
K
E
D
D
K
T
R
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001090145
999
112576
G123
N
V
N
G
E
Q
V
G
H
I
K
K
E
L
A
Zebra Danio
Brachydanio rerio
XP_693071
942
104740
Y115
E
L
A
A
A
M
A
Y
I
M
D
N
K
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P34739
1061
118357
E144
D
L
S
D
D
D
S
E
I
E
Y
S
D
E
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786706
1093
121576
Y153
G
L
A
E
V
L
S
Y
I
V
D
N
N
Y
A
Poplar Tree
Populus trichocarpa
XP_002308876
799
88908
V13
E
S
F
M
V
G
F
V
I
A
N
I
V
G
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FF61
881
98598
N95
P
L
N
V
Y
D
N
N
A
I
R
V
L
N
T
Baker's Yeast
Sacchar. cerevisiae
P31244
790
91412
Red Bread Mold
Neurospora crassa
Q7S1P9
1222
137173
S155
F
V
G
E
K
V
A
S
D
I
L
H
V
I
S
Conservation
Percent
Protein Identity:
100
99.5
N.A.
85.5
N.A.
83.6
81.4
N.A.
71.7
N.A.
64.3
53.1
N.A.
21.1
N.A.
N.A.
34.5
Protein Similarity:
100
99.8
N.A.
88
N.A.
89.7
87.9
N.A.
78.5
N.A.
79.3
69.8
N.A.
41.2
N.A.
N.A.
53.1
P-Site Identity:
100
100
N.A.
86.6
N.A.
80
0
N.A.
13.3
N.A.
20
86.6
N.A.
13.3
N.A.
N.A.
53.3
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
6.6
N.A.
20
N.A.
40
93.3
N.A.
40
N.A.
N.A.
66.6
Percent
Protein Identity:
33.6
N.A.
N.A.
36
22.7
25.2
Protein Similarity:
50.4
N.A.
N.A.
52.7
40.9
43.9
P-Site Identity:
13.3
N.A.
N.A.
6.6
0
6.6
P-Site Similarity:
20
N.A.
N.A.
13.3
0
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
43
22
36
0
43
0
8
8
0
0
0
0
50
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
8
0
8
8
15
8
0
8
0
50
8
8
8
0
% D
% Glu:
36
0
0
15
8
8
0
8
0
15
0
0
8
8
0
% E
% Phe:
15
0
8
0
8
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
8
22
8
8
0
8
8
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
8
8
0
8
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
58
22
0
8
0
8
0
% I
% Lys:
0
0
8
0
8
0
0
0
8
0
8
15
43
0
0
% K
% Leu:
0
50
0
8
0
29
0
8
0
0
15
0
8
43
15
% L
% Met:
0
0
0
8
0
8
0
0
0
36
0
0
0
0
0
% M
% Asn:
15
8
15
8
0
8
8
8
0
0
8
43
8
8
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
8
% R
% Ser:
0
8
8
0
0
0
15
8
0
0
0
8
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% T
% Val:
0
15
8
8
15
15
8
15
0
8
0
8
15
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
43
0
0
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _